SCHEMBL10153148

SCHEMBL10153148

CC1(C)c2cc(-c3c4ccccc4c(-c4cccnc4)c4ccccc34)ccc2-c2ccc(-c3c4ccccc4c(-c4cccnc4)c4ccccc34)cc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.47
CYP11B1 P15538 6/20 0.44
CYP11B2 P19099 6/20 0.40
CYP19A1 P11511 2/20 0.40
CYP17A1 P05093 1/20 0.40
TDP2 O95551 1/20 0.39
CYP2A6 P11509 4/20 0.39
CYP1A2 P05177 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
DHODH Q02127 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
PTGS2 P35354 1/20 0.38
IDO1 P14902 1/20 0.37
LRRK2 Q5S007 1/20 0.37
CYP2E1 P05181 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2B6 P20813 1/20 0.37
CYP2C19 P33261 1/20 0.37
ALK Q9UM73 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13488129 0.91 PDK2 (0.49) PDK2CYP11B1CYP11B2CYP19A1CYP17A1
SCHEMBL13487899 0.89 PDK2 (0.47) PDK2CYP11B1CYP11B2CYP19A1CYP17A1
SCHEMBL24433132 0.88 CYP11B1 (0.41) PDK2CYP11B1CYP19A1CYP1A2ALDH1A1
SCHEMBL13487838 0.88 PDK2 (0.44) PDK2CYP11B1CYP17A1CYP2A6ALDH1A1
SCHEMBL13487757 0.88 PDK2 (0.46) PDK2CYP11B1CYP11B2CYP19A1CYP17A1
SCHEMBL15977617 0.88 PDK2 (0.51) PDK2CYP11B1CYP11B2CYP19A1CYP17A1
SCHEMBL1102673 0.86 PDK2 (0.37) PDK2CYP11B1CYP17A1CYP1A2DHODH
SCHEMBL15908009 0.86 CYP11B2 (0.49) PDK2CYP11B1CYP11B2CYP19A1CYP17A1
SCHEMBL13488052 0.85 CYP11B2 (0.49) PDK2CYP11B1CYP11B2CYP19A1CYP17A1
SCHEMBL13487981 0.85 PDK2 (0.42) PDK2CYP11B1CYP11B2CYP19A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed