SCHEMBL15908009

SCHEMBL15908009

CC1(C)c2cc(-c3c4ccccc4c(-c4ccc5cc(-c6cccnc6)ccc5c4)c4ccccc34)ccc2-c2cc3c4ccccc4c4ccccc4c3cc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 12/20 0.49
CYP11B1 P15538 12/20 0.49
CYP19A1 P11511 8/20 0.49
CYP17A1 P05093 6/20 0.49
PDK2 Q15119 1/20 0.44
PGR P06401 1/20 0.38
DYRK3 O43781 1/20 0.38
JAK2 O60674 1/20 0.38
ROCK2 O75116 1/20 0.38
PRKD3 O94806 1/20 0.38
MAP4K4 O95819 1/20 0.38
CDK1 P06493 1/20 0.38
PIM1 P11309 1/20 0.38
CDK2 P24941 1/20 0.38
MAPK1 P28482 1/20 0.38
AKT2 P31751 1/20 0.38
FLT4 P35916 1/20 0.38
CDK8 P49336 1/20 0.38
CLK2 P49760 1/20 0.38
GSK3B P49841 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153148 0.86 PDK2 (0.47) CYP11B2CYP11B1CYP19A1CYP17A1PDK2
SCHEMBL13488052 0.84 CYP11B2 (0.49) CYP11B2CYP11B1CYP19A1CYP17A1PDK2
SCHEMBL25591788 0.82 LPL (0.38) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A2
SCHEMBL15977617 0.82 PDK2 (0.51) CYP11B2CYP11B1CYP19A1CYP17A1PDK2
SCHEMBL1102782 0.81 CYP11B2 (0.43) CYP11B2CYP11B1CYP19A1CYP17A1PDK2
SCHEMBL24433238 0.81 PDK2 (0.43) CYP11B2CYP11B1CYP19A1CYP17A1PDK2
SCHEMBL13488129 0.81 PDK2 (0.49) CYP11B2CYP11B1CYP19A1CYP17A1PDK2
SCHEMBL1102596 0.81 PDK2 (0.39) CYP11B2CYP11B1CYP19A1CYP17A1PDK2
SCHEMBL13388789 0.80 PDK2 (0.57) CYP11B2CYP11B1CYP19A1CYP17A1PDK2
SCHEMBL1102676 0.80 CYP11B1 (0.41) CYP11B2CYP11B1CYP19A1CYP17A1CDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9048437-B2 Organic compound for organic electroluminescent device NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2015-06-02 US disclosed
US-9048437-B2 Organic compound for organic electroluminescent device NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2015-06-02 US disclosed
US-20140209866-A1 ORGANIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2014-07-31 US disclosed
US-20140209866-A1 ORGANIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2014-07-31 US disclosed