Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14248201 | 0.88 | GAA (0.55) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL10129233 | 0.85 | GAA (0.59) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL10113793 | 0.82 | MAPT (0.65) | GAAMAPTMEN1KMT2ARXFP1 | |
| SCHEMBL2267031 | 0.82 | GAA (0.50) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL19732951 | 0.81 | GAA (0.67) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL13118736 | 0.81 | TDP1 (0.57) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL19732950 | 0.81 | GAA (0.67) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL19732957 | 0.81 | GAA (0.67) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL2647640 | 0.78 | CACNA1F (0.44) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL10330877 | 0.78 | TDP1 (0.53) | GAAMAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423195-A1 | Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof | LEK Pharmaceuticals d.d. (SI) | 2012-02-29 | — | — | EP | disclosed |