Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10153183 | 0.88 | GAA (0.56) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL10129233 | 0.84 | GAA (0.59) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL2267031 | 0.81 | GAA (0.50) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL10113793 | 0.81 | MAPT (0.65) | GAAMAPTMEN1KMT2ACA12 | |
| SCHEMBL13118736 | 0.80 | TDP1 (0.57) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL10330877 | 0.77 | TDP1 (0.53) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL10129482 | 0.76 | TDP1 (0.51) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL19732957 | 0.71 | GAA (0.67) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL19732950 | 0.71 | GAA (0.67) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL19732951 | 0.71 | GAA (0.67) | GAAMAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012172564-A1 | PROCESS FOR PREPARATION OF ROSUVASTATIN CALCIUM | DR. REDDY'S LABORATORIES LIMITED (IN) | 2012-12-20 | — | — | WO | claimed |
| WO-2012172564-A1 | PROCESS FOR PREPARATION OF ROSUVASTATIN CALCIUM | DR. REDDY'S LABORATORIES LIMITED (IN) | 2012-12-20 | — | — | WO | disclosed |