SCHEMBL10153409

SCHEMBL10153409

c1ccc2c(c1)c1cccc3c1n2CC3

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.56
LMNA P02545 2/20 0.56
MEN1 O00255 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
PIM1 P11309 3/20 0.43
PIM3 Q86V86 3/20 0.43
PIM2 Q9P1W9 1/20 0.43
LIPG Q9Y5X9 1/20 0.43
CDK4 P11802 1/20 0.41
CCND1 P24385 1/20 0.41
HSD17B10 Q99714 3/20 0.41
ALDH1A1 P00352 2/20 0.41
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
KDM4E B2RXH2 6/20 0.40
HTR2A P28223 3/20 0.40
MAPT P10636 2/20 0.40
ADRA2A P08913 2/20 0.40
ADRA2B P18089 2/20 0.40
ADRA2C P18825 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1099540 0.89 HSD17B10 (0.53) KMT2ALMNAMEN1TDP1PIM1
SCHEMBL11881460 0.78 HTR2C (0.61) KMT2AMEN1TDP1LIPGCDK4
SCHEMBL6981939 0.75 PIM1 (0.42) KMT2AMEN1PIM1PIM3PIM2
SCHEMBL4488500 0.74 ALKBH5 (0.37) KMT2ALMNAMEN1TDP1PIM1
SCHEMBL13703804 0.72 KDM4E (0.55) KMT2ALMNAMEN1PIM1PIM3
SCHEMBL3539313 0.72 HTR2C (0.69) KMT2ALMNAMEN1TDP1HSD17B10
SCHEMBL3542992 0.72 HTR2C (0.69) KMT2ALMNAMEN1TDP1HSD17B10
SCHEMBL11842314 0.70 KMT2A (0.66) KMT2ALMNAMEN1TDP1LIPG
SCHEMBL31318489 0.70 KDM4E (0.51) KMT2AMEN1TDP1HSD17B10ALDH1A1
SCHEMBL6500842 0.69 HTR2C (0.63) KMT2ALMNAMEN1TDP1CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023181958-A1 LIGHT-EMITTING ELEMENT AND PRODUCTION METHOD THEREFOR, LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD THEREFOR, COMPOSITION AND PRODUCTION METHOD THEREFOR, INFORMATION PROCESSING METHOD, INFORMATION PROCESSING DEVICE, PROGRAM, METHOD FOR PROVIDING LIGHT-EMITTING COMPOUND, AND DATA GENERATION METHOD 住友化学株式会社 2023-09-28 WO disclosed
US-20160293853-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-10-06 US disclosed
US-8421066-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2013-04-16 US disclosed
US-20120178928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-8174002-B2 Organic electroluminescence device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-20100051928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CHRM1, LEF1 KMT2A 1575/4885LMNA 962/4885MEN1 200/4885
US-20160293853-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, JUND KMT2A 1297/4885LMNA 4385/4885MEN1 4553/4885
US-20120178928-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CHRM1, LEF1 KMT2A 1575/4885LMNA 962/4885MEN1 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.