Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31653964 | 0.99 | TSHR (0.59) | TSHRHTTL3MBTL1GAATP53 | |
| SCHEMBL9958705 | 0.80 | HDAC4 (0.62) | TSHRHTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL19380274 | 0.79 | HDAC4 (0.44) | TSHRHTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL10154010 | 0.78 | MAPT (0.44) | TSHRHTTL3MBTL1MAPTTHRB | |
| SCHEMBL9958546 | 0.78 | TSHR (0.48) | TSHRHTTL3MBTL1GAATP53 | |
| SCHEMBL31653962 | 0.77 | MEN1 (0.47) | L3MBTL1GAALMNANPSR1 | |
| SCHEMBL10153609 | 0.77 | MEN1 (0.47) | L3MBTL1GAALMNANPSR1 | |
| SCHEMBL10153606 | 0.76 | KCNA5 (0.48) | L3MBTL1GAALMNAMAPT | |
| SCHEMBL31653994 | 0.76 | KCNA5 (0.48) | L3MBTL1GAALMNAMAPT | |
| SCHEMBL11789850 | 0.75 | ALDH1A1 (0.43) | HTTGAAALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085003-A1 | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AND RELATED COMPOUNDS USEFUL AS HIV REPLICATION INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2012-06-28 | — | — | WO | disclosed |