SCHEMBL10154044

SCHEMBL10154044

O=C1C2CC3CC1CC(OC(=O)C(F)(F)S)(C3)C2

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
EPHX2 P34913 2/20 0.41
CYP19A1 P11511 2/20 0.36
CYP17A1 P05093 1/20 0.36
NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26011995 0.88 TSHR (0.51) TSHRNPSR1EPHX2CYP19A1CYP17A1
SCHEMBL685366 0.85 TSHR (0.53) TSHRNPSR1EPHX2CYP19A1CYP17A1
SCHEMBL685847 0.85 TSHR (0.53) TSHRNPSR1EPHX2CYP19A1CYP17A1
SCHEMBL547287 0.84 TSHR (0.52) TSHRNPSR1EPHX2CYP19A1CYP17A1
SCHEMBL19261603 0.84 TSHR (0.52) TSHRNPSR1EPHX2CYP19A1CYP17A1
SCHEMBL14035930 0.83 TSHR (0.49) TSHRNPSR1EPHX2CYP19A1CYP17A1
SCHEMBL24361264 0.82 TSHR (0.51) TSHRNPSR1EPHX2CYP19A1CYP17A1
SCHEMBL685848 0.82 TSHR (0.51) TSHRNPSR1EPHX2CYP19A1CYP17A1
SCHEMBL14554274 0.82 TSHR (0.51) TSHRNPSR1EPHX2CYP19A1CYP17A1
SCHEMBL10150821 0.82 TSHR (0.51) TSHRNPSR1EPHX2CYP19A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130022923-A1 RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-24 US disclosed
US-20130022916-A1 RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-24 US disclosed
US-20130022916-A1 RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-24 US disclosed
US-20120270154-A1 RESIN AND PHOTORESIST COMPOSITION COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-25 US disclosed
US-20120088190-A1 SALT AND PHOTORESIST COMPOSITION COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-12 US disclosed
US-20110053082-A1 RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-03 US disclosed
US-20100330497-A1 CHEMICALLY AMPLIFIED PHOTORESIST COMPOSITION AND METHOD FOR FORMING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088190-A1 SALT AND PHOTORESIST COMPOSITION COMPRISING THE SAME AFF1, FGFR1, FRG1 TSHR 834/4885NPSR1 1149/4885EPHX2 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.