FRG1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to FRG1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase 1/2 Study of FRF-001, an AAV-9 Gene Therapy, in Patients With FOXG1 Syndrome (FS)	PHASE1/PHASE2	NOT_YET_RECRUITING
Open Trail of γIFN for Friedreich Ataxia	PHASE2	COMPLETED
Folate Receptor Alpha Peptide Vaccine With GM-CSF in Patients With Triple Negative Breast Cancer	PHASE2	COMPLETED
Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer	PHASE2	ACTIVE_NOT_RECRUITING
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome	PHASE2	RECRUITING
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
[18F]-AZAFOL AS POSITRON EMISSION TOMOGRAPHY (PET) TRACER in FR Positive Cancer Imaging	PHASE1	COMPLETED
Methylprednisolone Treatment of Friedreich Ataxia	EARLY_PHASE1	COMPLETED
The Development of Human Immunologic Assays Specific to Folate Receptor Antigen	nan	UNKNOWN
Genetic Analysis of Fraser Syndrome and Fryns Syndrome	nan	COMPLETED
Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders	nan	RECRUITING
Neurogenetics Patient Registry	nan	RECRUITING
Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their Patents	nan	AVAILABLE
The Genetic Study of Primary Angle-Closure Glaucoma	nan	UNKNOWN
DeciFace: Decipher the Influence of Ethnic Backgrounds on the Facial Dysmorphic Features of Rare Mendelian Disorders	nan	RECRUITING
Amyotrophic Lateral Sclerosis (ALS) Families Project	nan	RECRUITING
Corrective Exercise and Rehabilitation in Fanconi Anemia: A Case Study	nan	COMPLETED
Collaborative Studies on the Genetics of Asthma (CSGA)	nan	COMPLETED
Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia	nan	RECRUITING
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives	nan	UNKNOWN
Gene Expression in Predicting Response to Paclitaxel in Patients With Breast Cancer	nan	UNKNOWN
A Study to Assess Variation in Potential Biomarkers in Friedreich Ataxia	nan	COMPLETED
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization	nan	COMPLETED
Efferocytosis and Genomic Polymorphism in Autoimmune Diseases	nan	UNKNOWN
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation	nan	UNKNOWN
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease	nan	COMPLETED
FRIEDREICH ATAXIA- STEROIDOGENESIS	nan	COMPLETED
Identification of New FTLD Genes	nan	UNKNOWN
Genetic Study of Familial Epilepsy	nan	COMPLETED
Finding Genes With NGS Techniques in Whom Mutations Cause Neurological Diseases	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a FRG1 binder may also engage these)

Protein	Name	Similarity
P97376	—	1.000	P97376 →
Q6GLS8	—	0.967	Q6GLS8 →
O73747	—	0.966	O73747 →
Q2HJ41	—	0.965	Q2HJ41 →
Q28C34	—	0.961	Q28C34 →
Q9TS33	—	0.959	Q9TS33 →
Q8BM39	—	0.959	Q8BM39 →
Q6GMH0	—	0.958	Q6GMH0 →
Q9JKB8	—	0.958	Q9JKB8 →
Q5RE03	—	0.958	Q5RE03 →
Q99633	—	0.958	Q99633 →
Q66H99	—	0.958	Q66H99 →
Q5EAV6	—	0.958	Q5EAV6 →
A2AGL3	—	0.958	A2AGL3 →
Q8QFR2	—	0.958	Q8QFR2 →
P30957	—	0.958	P30957 →
RYR2	Ryanodine receptor 2	0.958	landscape →
Q6NRD0	—	0.957	Q6NRD0 →
Q6P4T2	—	0.957	Q6P4T2 →
EIF3A	Eukaryotic translation initiation factor 3 subunit A	0.957	landscape →
B0LPN4	—	0.957	B0LPN4 →
SNRNP200	U5 small nuclear ribonucleoprotein 200 kDa helicase	0.956	landscape →
P29540	—	0.956	P29540 →
Q5R644	—	0.956	Q5R644 →
Q8N6S4	—	0.956	Q8N6S4 →
PRPF3	U4/U6 small nuclear ribonucleoprotein Prp3	0.956	landscape →
Q1JU68	—	0.955	Q1JU68 →
Q15413	—	0.955	Q15413 →
Q5ZMW3	—	0.955	Q5ZMW3 →
Q07866	—	0.955	Q07866 →