Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120830 | 0.88 | TMPRSS2 (0.46) | TMPRSS2CSNK2A2CSNK2A1POLRMTRIPK1 | |
| SCHEMBL18310024 | 0.86 | TMPRSS2 (0.46) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL24119259 | 0.86 | TMPRSS2 (0.39) | TMPRSS2CSNK2A2CSNK2A1POLRMTRIPK1 | |
| SCHEMBL20144212 | 0.85 | TMPRSS2 (0.37) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL10154374 | 0.85 | TMPRSS2 (0.33) | TMPRSS2CSNK2A2CSNK2A1POLRMTRIPK1 | |
| SCHEMBL20078711 | 0.84 | TMPRSS2 (0.33) | TMPRSS2CSNK2A2CSNK2A1RIPK1 | |
| SCHEMBL21283650 | 0.84 | CYP3A4 (0.33) | TMPRSS2RIPK1 | |
| SCHEMBL24789693 | 0.84 | POLRMT (0.38) | TMPRSS2CSNK2A2CSNK2A1POLRMT | |
| SCHEMBL24606306 | 0.83 | TMPRSS2 (0.41) | TMPRSS2CSNK2A2CSNK2A1POLRMTRIPK1 | |
| SCHEMBL10154106 | 0.83 | CYP3A4 (0.34) | TMPRSS2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049060-A1 | METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |
| WO-2012012776-A1 | METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2012-01-26 | — | — | WO | disclosed |