Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530208 | 0.81 | TRPV1 (0.53) | MGAMMETTL3KDM2BTRPV1CFTR | |
| Hydrochloric Acid SCHEMBL530298 | 0.80 | TRPV1 (0.52) | MGAMMETTL3KDM2BTRPV1CFTR | |
| SCHEMBL8021165 | 0.79 | KMT2A (0.49) | MGAMMETTL3KDM2BTRPV1CHRNB2 | |
| SCHEMBL10154201 | 0.79 | KDM2B (0.63) | MGAMMETTL3KDM2BTRPV1CFTR | |
| SCHEMBL29171624 | 0.79 | PTPN1 (0.54) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2906679 | 0.78 | KDM4E (0.50) | KDM2BCHRNB2CHRNA7CHRNA4MEN1 | |
| SCHEMBL11175090 | 0.76 | KMT2A (0.65) | MGAMKDM2BTRPV1CFTRCHRNB2 | |
| SCHEMBL531094 | 0.76 | HPGDS (0.72) | MGAMTRPV1NPC1KMT2AHPGDS | |
| SCHEMBL529904 | 0.75 | MGAM (0.65) | MGAMCFTRNPC1ALDH1A1RAB9A | |
| SCHEMBL8270577 | 0.75 | MGAM (0.65) | MGAMTRPV1CFTRCHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110683-B2 | Piperidinyl compounds that selectively bind integrins | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-02-07 | — | — | US | disclosed |
| US-20110092528-A1 | PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | DE CORTE BART | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092528-A1 | PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | ITGB3, ITGAV, ITGA2B | MGAM 4706/4885METTL3 4587/4885KDM2B 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.