SCHEMBL1015476

SCHEMBL1015476

CCCCOC1=CC2CCC1C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.38
RAB9A P51151 2/20 0.38
TSHR P16473 1/20 0.32
CYP2D6 P10635 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CRBN Q96SW2 1/20 0.31
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
LTA4H P09960 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C9 P11712 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155171 0.70 SPHK1 (0.33)
SCHEMBL9625158 0.70 CYP19A1 (0.57) CYP19A1RAB9AMEN1ALDH1A1KMT2A
SCHEMBL2309926 0.68
SCHEMBL2313847 0.68
SCHEMBL2315400 0.68
SCHEMBL153537 0.68 SPHK1 (0.41) ALDH1A1ADRB3CHRM2CHRM5CHRM1
SCHEMBL649223 0.68 SPHK1 (0.41) ALDH1A1ADRB3CHRM2CHRM5CHRM1
SCHEMBL1011862 0.68 SPHK1 (0.41) ALDH1A1ADRB3CHRM2CHRM5CHRM1
SCHEMBL5898950 0.68 SPHK1 (0.41) ALDH1A1ADRB3CHRM2CHRM5CHRM1
SCHEMBL152342 0.68 SPHK1 (0.41) ALDH1A1ADRB3CHRM2CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170233876-A1 ELECTROLYTIC CELL COVERS COMPRISING A RESIN COMPOSITION POLYMERIZED WITH A GROUP 8 OLEFIN METATHESIS CATALYST MATERIA, INC. (US) 2017-08-17 US disclosed
EP-2756112-B1 IMPROVED ELECTROLYTIC CELL COVERS COMPRISING A RESIN COMPOSITION POLYMERIZED WITH A GROUP 8 OLEFIN METATHESIS CATALYST MATERIA INC (US) 2017-04-05 EP disclosed
US-20150165652-A1 ELECTROLYTIC CELL COVERS COMPRISING A RESIN COMPOSITION POLYMERIZED WITH A GROUP 8 OLEFIN METATHESIS CATALYST MATERIA, INC. (US) 2015-06-18 US disclosed
EP-2756112-A2 IMPROVED ELECTROLYTIC CELL COVERS COMPRISING A RESIN COMPOSITION POLYMERIZED WITH A GROUP 8 OLEFIN METATHESIS CATALYST Materia, Inc. (US) 2014-07-23 EP disclosed
WO-2013040519-A2 IMPROVED ELECTROLYTIC CELL COVERS COMPRISING A RESIN COMPOSITION POLYMERIZED WITH A GROUP 8 OLEFIN METATHESIS CATALYST MATERIA, INC. (US) 2013-03-21 WO disclosed
US-20120241250-A1 Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers EAKIN GEORGE R (US) 2012-09-27 US disclosed
EP-1372844-B1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2011-01-05 EP disclosed
EP-1372844-A4 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2005-10-12 EP disclosed
US-6936672-B2 Mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO., LTD. (JP) 2005-08-30 US disclosed
EP-1155057-B1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES SUMITOMO BAKELITE CO (JP) 2005-06-22 EP disclosed
US-20030083445-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor STERLING JA, L.C. 2003-05-01 US disclosed
US-6538087-B2 (hetero)polycyclic polymer PROMERUS, LLC 2003-03-25 US disclosed
WO-2002076613-A1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-10-03 WO disclosed
US-20020103317-A1 Polymeric compositions for forming optical waveguides; optical waveguides formed therefrom; and methods for making same SUMITOMO BAKELITE CO., LTD. (JP) 2002-08-01 US disclosed
US-20020064896-A1 Optical waveguides and methods for making the same 3M INNOVATIVE PROPERTIES COMPANY 2002-05-30 US disclosed
US-6350832-B1 CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION THE B. F. GOODRICH COMPANY 2002-02-26 US disclosed
WO-2002010231-A2 POLYMERIC COMPOSITIONS FOR FORMING OPTICAL WAVEGUIDES; OPTICAL WAVEGUIDES FORMED THEREFROM; AND METHODS FOR MAKING SAME GOODRICH CORPORATION (US) 2002-02-07 WO disclosed
CN-1333788-A In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes GOODRICH CO B F (US) 2002-01-30 CN disclosed
EP-1155057-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES The B.F.Goodrich Co. (US) 2001-11-21 EP disclosed
WO-2000034344-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES THE B.F.GOODRICH COMPANY (US) 2000-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030083445-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor NQO1, NIT2, ALOX5 CYP19A1 226/4885RAB9A 3978/4885TSHR 4822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.