Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.44 |
| ▸ | CDC7 | O00311 | 3/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | PIKFYVE | Q9Y2I7 | 4/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154869 | 0.88 | KDR (0.56) | KDRMAPKAPK2MAPK9DYRK1AWNT1 | |
| SCHEMBL10154871 | 0.88 | KDR (0.60) | KDRMAPKAPK2CDC7MAPK9PIKFYVE | |
| SCHEMBL10154873 | 0.80 | KDR (0.57) | KDRMAPKAPK2PIKFYVE | |
| SCHEMBL10154875 | 0.77 | KDR (0.70) | KDRMAPKAPK2PRKD1 | |
| SCHEMBL10154866 | 0.77 | KDR (0.66) | KDRMAPKAPK2PRKD1MAP3K14 | |
| SCHEMBL12351904 | 0.77 | KDR (0.66) | KDRDYRK1APRKD1MAP3K14PIM1 | |
| SCHEMBL10154870 | 0.77 | KDR (0.66) | KDRPRKD1 | |
| SCHEMBL10155125 | 0.75 | SIRT2 (0.54) | PIKFYVEDYRK1APIM1PIM3 | |
| SCHEMBL619090 | 0.73 | KDR (0.60) | KDRPRKD1 | |
| SCHEMBL1004259 | 0.69 | KDR (0.55) | KDRMAPKAPK2CDC7PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040965-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | BORISOVICH FROLOV YEVGENIY (RU) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040965-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | ABCG2, HTR3C, AADAC | KDR 2394/4885MAPKAPK2 4413/4885CDC7 2726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.