Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | CDC7 | O00311 | 4/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154864 | 0.88 | KDR (0.58) | KDRCDC7MAPKAPK2PKN2CLK2 | |
| SCHEMBL10154869 | 0.85 | KDR (0.56) | KDRPDE3BPDE3AMAPKAPK2CDK9 | |
| SCHEMBL10154873 | 0.81 | KDR (0.57) | KDRMAPKAPK2PIKFYVE | |
| SCHEMBL10154870 | 0.79 | KDR (0.66) | KDRCDK5PRKD1 | |
| SCHEMBL10154875 | 0.79 | KDR (0.70) | KDRMAPKAPK2ROCK2MAPK1PRKD1 | |
| SCHEMBL10154866 | 0.79 | KDR (0.66) | KDRMAPKAPK2CDK1CDK2MAPK1 | |
| SCHEMBL12351904 | 0.79 | KDR (0.66) | KDRPKN2ROCK2RPS6KB1CDK2 | |
| SCHEMBL10155121 | 0.75 | SIRT2 (0.55) | CDC7PDE3BPDE3APKN2PIM3 | |
| SCHEMBL619090 | 0.75 | KDR (0.60) | KDRPRKD3PRKACAJAK3PRKCQ | |
| SCHEMBL1004259 | 0.70 | KDR (0.55) | KDRCDC7MAPKAPK2CDK9CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040965-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | BORISOVICH FROLOV YEVGENIY (RU) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040965-A1 | SUBSTITUTED AZEPINO[4,3-B]INDOLES, PHARMACOLOGICAL COMPOSITION AND A METHOD FOR THE PRODUCTION AND USE THEREOF | ABCG2, HTR3C, AADAC | KDR 2394/4885CDC7 2726/4885PDE3B 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.