SCHEMBL10154993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10156628	0.89	BACE1 (0.55)	KMT2ATSHRGAAGLABACE1
	SCHEMBL10155005	0.83	BACE1 (0.48)	BACE1
	SCHEMBL14143726	0.82	BACE1 (0.45)	BACE1
	SCHEMBL10155525	0.81	BACE1 (0.56)	BACE1HPGDALDH1A1
	SCHEMBL10155024	0.81	BACE1 (0.54)	BACE1HPGDALDH1A1
	SCHEMBL10157290	0.81	BACE1 (0.54)	BACE1HPGDALDH1A1
	SCHEMBL10157567	0.80	ALDH1A1 (0.52)	KMT2ATSHRGAABACE1TP53
	SCHEMBL10155407	0.77	BACE1 (0.47)	BACE1
	SCHEMBL10155579	0.76	POLB (0.50)	KMT2ABACE1POLBHPGD
	SCHEMBL10155461	0.75	BACE1 (0.57)	KMT2ATSHRBACE1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.