SCHEMBL10155461

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10156396	0.91	BACE1 (0.47)	BACE1POLBKMT2AALDH1A1LMNA
	SCHEMBL10157967	0.90	SMN1; SMN2 (0.52)	BACE1POLBMEN1KMT2ASLC6A7
	SCHEMBL10155537	0.89	BACE1 (0.54)	BACE1TSHRALDH1A1USP2LMNA
	SCHEMBL10154605	0.88	BACE1 (0.55)	BACE1KMT2ACA12CA1CA2
	SCHEMBL10156336	0.87	BACE1 (0.51)	BACE1MEN1KMT2ATSHRALDH1A1
	SCHEMBL10156279	0.87	BACE1 (0.51)	BACE1POLBMEN1KMT2ATSHR
	SCHEMBL10155033	0.87	L3MBTL1 (0.52)	BACE1SLC6A7TSHRALDH1A1CYP2C9
	SCHEMBL10157908	0.86	KDM4E (0.54)	BACE1POLBMEN1KMT2ATSHR
	SCHEMBL10157501	0.86	KDM4E (0.57)	BACE1POLBMEN1KMT2ASLC6A7
	SCHEMBL10155525	0.86	BACE1 (0.56)	BACE1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.