SCHEMBL1015508

SCHEMBL1015508

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCOc1cc(Br)cc(Br)c1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.32
SOD1 P00441 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3480923 0.83 MAOB (0.31) MAOB
SCHEMBL3480730 0.78 CNR1 (0.31) MAOB
SCHEMBL4870514 0.77 ATM (0.42) MAOB
SCHEMBL5959986 0.77 KCNA3 (0.50)
SCHEMBL1751270 0.76 APP (0.34) MAOB
SCHEMBL5489747 0.74 MAOB (0.35) MAOB
SCHEMBL4870458 0.74 KDM4E (0.40)
SCHEMBL19092734 0.72 SOD1 (0.44) MAOBSOD1
SCHEMBL3779536 0.72 HRH3 (0.42) MAOB
SCHEMBL15387091 0.72 PPARA (0.34) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272851-B1 FLUORINATED BORONIC ACID ESTER COMPOUND AND PROCESS FOR PRODUCTION THEREOF UNIMATEC CO LTD (JP) 2014-02-26 EP disclosed
US-7951964-B2 Fluorine-containing boronic acid ester compound and method for producing the same UNIMATEC CO., LTD. (JP) 2011-05-31 US disclosed
US-7951964-B2 Fluorine-containing boronic acid ester compound and method for producing the same UNIMATEC CO., LTD. (JP) 2011-05-31 US disclosed
US-20110040118-A1 FLUORINE-CONTAINING BORONIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME UNIMATEC CO., LTD. (JP) 2011-02-17 US disclosed
US-20110040118-A1 FLUORINE-CONTAINING BORONIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME UNIMATEC CO., LTD. (JP) 2011-02-17 US disclosed
EP-2272851-A1 FLUORINATED BORONIC ACID ESTER COMPOUND AND PROCESS FOR PRODUCTION THEREOF Unimatec Co., Ltd. (JP) 2011-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110040118-A1 FLUORINE-CONTAINING BORONIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME BCL6, AFF1, TLR7 MAOB 1541/4885SOD1 2927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.