Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424352 | 1.00 | HRH3 (0.42) | HRH3LTA4HMEN1KMT2APPARA | |
| SCHEMBL27096233 | 0.98 | HRH3 (0.43) | HRH3LTA4HMEN1KMT2APPARA | |
| SCHEMBL12101371 | 0.87 | HRH3 (0.46) | HRH3LTA4HMEN1KMT2APPARA | |
| SCHEMBL1751270 | 0.86 | APP (0.34) | APPMAOB | |
| SCHEMBL3480730 | 0.85 | CNR1 (0.31) | MAOB | |
| SCHEMBL5489747 | 0.81 | MAOB (0.35) | PPARAMAOB | |
| SCHEMBL5959986 | 0.81 | KCNA3 (0.50) | LTA4HPPARA | |
| SCHEMBL18028239 | 0.81 | PSMB1 (0.41) | HRH3PPARA | |
| SCHEMBL9141866 | 0.79 | NR5A1 (0.50) | LTA4HAPP | |
| SCHEMBL19460833 | 0.78 | S1PR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11167277-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200398262-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-24 | — | — | US | disclosed |
| US-10758895-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2020-09-01 | — | — | US | disclosed |
| US-20170297008-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCACATION (US) | 2017-10-19 | — | — | US | disclosed |
| US-20150225339-A1 | FLUORINATED POLYMERIZABLE COMPOUND | BASF SE (DE) | 2015-08-13 | — | — | US | disclosed |
| US-20100324205-A1 | FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2010-12-23 | — | — | US | disclosed |
| US-20090240004-A1 | FUNCTIONALIZED POLYURETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2009-09-24 | — | — | US | disclosed |
| US-20090198000-A1 | Liquid fluorine-containing and two-component compositions for the surface treatment of mineral and non-mineral substrates | EVONIK DEGUSSA GMBH (DE) | 2009-08-06 | — | — | US | disclosed |
| EP-2085442-A1 | Compounds containing fluoride with improved surface characteristics | Evonik Degussa GmbH (DE) | 2009-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200398262-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | RNGTT, AOC2, CTRC | HRH3 3427/4885LTA4H 2475/4885MEN1 3749/4885 |
| US-10758895-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | RNGTT, AOC2, CTRC | HRH3 3427/4885LTA4H 2475/4885MEN1 3749/4885 |
| US-11167277-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | RNGTT, AOC2, CTRC | HRH3 3427/4885LTA4H 2475/4885MEN1 3749/4885 |
| US-20150225339-A1 | FLUORINATED POLYMERIZABLE COMPOUND | FRK, AFF2, AFF1 | HRH3 126/4885LTA4H 3751/4885MEN1 1984/4885 |
| US-20170297008-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | RNGTT, AOC2, CTRC | HRH3 3427/4885LTA4H 2475/4885MEN1 3749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.