SCHEMBL10155562

SCHEMBL10155562

C=C1C(=O)C(C)=C1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19983586 0.86 CTSD (0.38)
SCHEMBL13431173 0.80 DUSP3 (0.39)
SCHEMBL10035859 0.71
SCHEMBL12156967 0.71
Duroquinone SCHEMBL58325 0.71 MAOA (0.38)
SCHEMBL14459682 0.68
SCHEMBL13581861 0.68 MAOA (0.36)
SCHEMBL10486657 0.68 MAOA (0.36)
Duroquinone SCHEMBL11473070 0.68 MAOA (0.36)
SCHEMBL18213670 0.67 CTSD (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151059-A1 IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2023-05-18 US disclosed
US-20170084839-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2017-03-23 US disclosed
US-8624035-B2 Functionalized cyanine having a silane linker arm, a method of preparing thereof and uses thereof UNIVERSITA' DEGLI STUDI DI TORINO (IT) 2014-01-07 US disclosed
US-8524732-B2 Substituted tetrahydroquinolines MERCK PATENT GMBH (DE) 2013-09-03 US disclosed
US-8193164-B2 Organic compounds NOVARTIS AG (CH) 2012-06-05 US disclosed
US-8034626-B2 Labels, their production process and their uses LABORATOIRES SYNTH-INNOVE (FR) 2011-10-11 US disclosed
US-20100190784-A1 Organic Compounds NOVARTIS AG 2010-07-29 US disclosed
US-20100129293-A1 Near Infrared Imaging Agent INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) 2010-05-27 US disclosed
US-7655217-B2 Near infrared imaging agent Institut fur Diagnosikforschung GmbH (DE) 2010-02-02 US disclosed
US-20100022579-A1 SUBSTITUTED TETRAHYDROQUINOLINES Merck Patent Gesellschaft mit bescrankter Haftung (DE) 2010-01-28 US disclosed
US-20090148384-A1 FUNCTIONALIZED, SOLID POLYMER NANOPARTICLES COMPRISING EPOTHILONES BAYER SCHERING PHARMA AG (DE) 2009-06-11 US disclosed
US-7445767-B2 In-vivo diagnostic method by near infrared radiation INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) 2008-11-04 US disclosed
US-20080138820-A1 METHOD FOR DETERMINING GENOTOXICITY GE HEALTHCARE UK LIMITED (GB) 2008-06-12 US disclosed