SCHEMBL10155676

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10156604	0.89	BACE1 (0.54)	BACE1TSHRTP53ALDH1A1
	SCHEMBL10155525	0.84	BACE1 (0.56)	BACE1ALDH1A1
	SCHEMBL10155024	0.83	BACE1 (0.54)	BACE1ALDH1A1
	SCHEMBL10157290	0.83	BACE1 (0.54)	BACE1ALDH1A1CA12CA1CA2
	SCHEMBL10155461	0.82	BACE1 (0.57)	BACE1TSHRALDH1A1LMNACA12
	SCHEMBL10155033	0.81	L3MBTL1 (0.52)	BACE1TSHRALDH1A1
	SCHEMBL10155579	0.81	POLB (0.50)	BACE1
	SCHEMBL10156279	0.79	BACE1 (0.51)	BACE1TSHRALDH1A1GAANPSR1
	SCHEMBL10156336	0.79	BACE1 (0.51)	BACE1TSHRALDH1A1GAA
	SCHEMBL10155179	0.79	BACE1 (0.52)	BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.