SCHEMBL10156607

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10156455	0.83	BACE1 (0.61)	BACE1MEN1NPC1RAB9AKMT2A
	SCHEMBL10155385	0.83	BACE1 (0.72)	BACE1
	SCHEMBL10156025	0.81	BACE1 (0.69)	BACE1MEN1NPC1RAB9AKMT2A
	SCHEMBL10157469	0.76	BACE1 (0.68)	BACE1
	SCHEMBL10154679	0.76	BACE1 (1.00)	BACE1ALDH1A1KDM4E
	SCHEMBL10155418	0.74	BACE1 (0.65)	BACE1
	SCHEMBL10155344	0.74	BACE1 (0.62)	BACE1MEN1NPC1RAB9AKMT2A
	SCHEMBL10156621	0.73	BACE1 (0.67)	BACE1MEN1NPC1RAB9AKMT2A
	SCHEMBL10156334	0.73	BACE1 (0.61)	BACE1RAB9A
	SCHEMBL10155145	0.72	HSD17B1 (0.53)	BACE1NPC1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.