SCHEMBL10155145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10157314	0.90	HSD17B1 (0.59)	HSD17B1BACE1HSD17B2DYRK1A
	SCHEMBL10157519	0.88	SCD (0.65)	SCDBACE1KDM4ENPC1ALDH1A1
	SCHEMBL10156455	0.88	BACE1 (0.61)	SCDBACE1KDM4ENPC1RAB9A
	SCHEMBL10156252	0.87	HSD17B1 (0.62)	HSD17B1BACE1HSD17B2DYRK1ANPC1
	SCHEMBL10156620	0.80	NPC1 (0.57)	BACE1KDM4ENPC1ALDH1A1RAB9A
	SCHEMBL10156025	0.80	BACE1 (0.69)	SCDBACE1KDM4ENPC1RAB9A
	SCHEMBL10154789	0.79	SCD (0.63)	SCDBACE1KDM4ENPC1ALDH1A1
	SCHEMBL10155493	0.79	BACE1 (0.71)	BACE1
	SCHEMBL10157435	0.77	BACE1 (0.59)	BACE1
	SCHEMBL31024	0.77	HSD17B1 (0.82)	HSD17B1SCDHSD17B2DYRK1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.