SCHEMBL101567

SCHEMBL101567

C[Si](C)(C)C#CCCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8977890 0.83
SCHEMBL9445689 0.81
SCHEMBL4822542 0.81
SCHEMBL9560193 0.79 RAB9A (0.31)
SCHEMBL16487278 0.79 RAB9A (0.31)
SCHEMBL24235 0.75
SCHEMBL16420274 0.75 RAB9A (0.33)
Phosphine SCHEMBL10964059 0.73
SCHEMBL3474495 0.73
SCHEMBL10813046 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011012-A (S) -tert-butyl ((2-methyl-7- (trimethylsilyl) hept-6-alkyne-1-yl) oxy) diphenyl silane and synthesis method and application thereof 山东省农业科学院 2026-05-12 CN claimed
CN-113999104-A Synthesis method of commercial 7-alkyne-4-oxo-octanoic acid 西安康福诺生物科技有限公司 2022-02-01 CN claimed
CN-122011012-A (S) -tert-butyl ((2-methyl-7- (trimethylsilyl) hept-6-alkyne-1-yl) oxy) diphenyl silane and synthesis method and application thereof 山东省农业科学院 2026-05-12 CN disclosed
CN-119080602-A Preparation method of 7-alkyne-4-oxygen-octanoic acid 江苏南创化学与生命健康研究院有限公司 2024-12-06 CN disclosed
CN-111203277-B Application of chiral bidentate phosphite ligand, conia-Ene reaction catalyst and method for constructing chiral quaternary carbon center 郑州大学 2022-11-18 CN disclosed
WO-2022187693-A1 COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES UMBRA THERAPEUTICS INC. (US) 2022-09-09 WO disclosed
CN-113999104-A Synthesis method of commercial 7-alkyne-4-oxo-octanoic acid 西安康福诺生物科技有限公司 2022-02-01 CN disclosed
CN-113999104-A Synthesis method of commercial 7-alkyne-4-oxo-octanoic acid 西安康福诺生物科技有限公司 2022-02-01 CN disclosed
CN-111203277-A Application of chiral bidentate phosphite ligand, Conia-Ene reaction catalyst and method for constructing chiral quaternary carbon center 郑州大学 2020-05-29 CN disclosed
EP-2746268-B1 METHOD FOR CHEMICAL SYNTHESIS OF ANTROCIN YANG ZHEN (CN) 2016-12-07 EP disclosed
EP-2746268-B1 METHOD FOR CHEMICAL SYNTHESIS OF ANTROCIN YANG ZHEN (CN) 2016-12-07 EP disclosed
US-5073561-A N-substituted-pyridinyl oximes WARNER-LAMBERT COMPANY (US) 1991-12-17 US disclosed
US-4929734-A ANTIINFLAMMATORY AGENTS, ANTIDEPRESSANTS WARNER-LAMBERT COMPANY (US) 1990-05-29 US disclosed
US-4798841-A COGNITION ACTIVATORS, ANALGESICS WARNER-LAMBERT COMPANY (US) 1989-01-17 US disclosed
EP-0291673-A1 Tetrahydropyridine oximes, a process for their preparation and use thereof as cholinergic agents WARNER-LAMBERT COMPANY (US) 1988-11-23 EP disclosed
US-4710508-A ANALGESICS WARNER-LAMBERT COMPANY (US) 1987-12-01 US disclosed
US-4536592-A ANTISECRETORY AGENT G. D. SEARLE & CO. (US) 1985-08-20 US disclosed
US-4334088-A 2-Alkynyl-5-indanyloxyacetic acids MEAD JOHNSON & COMPANY (US) 1982-06-08 US disclosed
US-4291168-A DIURETICS MEAD JOHNSON & COMPANY (US) 1981-09-22 US disclosed
US-4247715-A BIURETICS MEAD JOHNSON & COMPANY (US) 1981-01-27 US disclosed