⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24235 | 0.97 | — | — | |
| Phosphine SCHEMBL10964059 | 0.94 | — | — | |
| SCHEMBL29930948 | 0.73 | — | — | |
| SCHEMBL101567 | 0.73 | — | — | |
| SCHEMBL9445689 | 0.73 | — | — | |
| SCHEMBL8977890 | 0.69 | — | — | |
| SCHEMBL4822542 | 0.67 | — | — | |
| SCHEMBL2830004 | 0.67 | — | — | |
| SCHEMBL9560193 | 0.66 | RAB9A (0.31) | — | |
| SCHEMBL16487278 | 0.66 | RAB9A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318960-B2 | Diarylphosphine- and dialkylphosphine-containing compounds, processes of preparing same and uses thereof as tridentate ligands | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2012-11-27 | — | — | US | disclosed |
| US-20100292084-A1 | NOVEL DIARYLPHOSPHINE- AND DIALKYLPHOSPHINE-CONTAINING COMPOUNDS, PROCESSES OF PREPARING SAME AND USES THEREOF AS TRIDENTATE LIGANDS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-11-18 | — | — | US | disclosed |
| US-20030144253-A1 | Acyclic and cyclic amine derivatives | VERTEX PHARMACEUTICALS INCORPORATED | 2003-07-31 | — | — | US | disclosed |
| EP-1207882-A4 | ACYCLIC AND CYCLIC AMINE DERIVATIVES | VERTEX PHARMA (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1207882-A1 | ACYCLIC AND CYCLIC AMINE DERIVATIVES | Vertex Pharmaceuticals Incorporated (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001008685-A1 | ACYCLIC AND CYCLIC AMINE DERIVATIVES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2001-02-08 | — | — | WO | disclosed |