Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 19/20 | 0.55 |
| ▸ | EGFR | P00533 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157157 | 0.88 | ROCK1 (0.50) | TNNI3KEGFRPOLB | |
| SCHEMBL10157834 | 0.86 | POLB (0.44) | TNNI3KEGFRPOLB | |
| SCHEMBL10156028 | 0.84 | POLB (0.43) | TNNI3KEGFRPOLB | |
| SCHEMBL10156550 | 0.77 | POLB (0.48) | TNNI3KPOLB | |
| SCHEMBL16305333 | 0.76 | TNNI3K (0.49) | TNNI3KEGFR | |
| SCHEMBL2227166 | 0.72 | TNNI3K (1.00) | TNNI3KEGFR | |
| SCHEMBL10156777 | 0.71 | POLB (0.42) | EGFRPOLB | |
| SCHEMBL12517924 | 0.71 | TNNI3K (0.79) | TNNI3KEGFR | |
| SCHEMBL17422233 | 0.70 | POLB (0.50) | POLB | |
| SCHEMBL8160226 | 0.70 | POLB (0.48) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | TNNI3K 1317/4885EGFR 28/4885POLB 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.