SCHEMBL10157501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10157095	0.90	HPGD (0.57)	KDM4EALDH1A1MAPK1HPGDSMN1; SMN2
	SCHEMBL10155033	0.89	L3MBTL1 (0.52)	KDM4EALDH1A1SLC6A7L3MBTL1CYP2C9
	SCHEMBL10155461	0.86	BACE1 (0.57)	ALDH1A1MAPK1SLC6A7CYP2C9SMN1; SMN2
	SCHEMBL10156336	0.83	BACE1 (0.51)	ALDH1A1SMN1; SMN2BACE1TSHRMEN1
	SCHEMBL10156279	0.83	BACE1 (0.51)	ALDH1A1MAPK1L3MBTL1SMN1; SMN2POLB
	SCHEMBL10157908	0.83	KDM4E (0.54)	KDM4EALDH1A1MAPK1CYP2C9SMN1; SMN2
	SCHEMBL10155525	0.82	BACE1 (0.56)	ALDH1A1HPGDBACE1
	SCHEMBL10155024	0.81	BACE1 (0.54)	ALDH1A1HPGDHSD17B10BACE1
	SCHEMBL10157290	0.81	BACE1 (0.54)	ALDH1A1HPGDBACE1
	SCHEMBL10156396	0.81	BACE1 (0.47)	KDM4EALDH1A1MAPK1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.