SCHEMBL10157519

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10154789	0.91	SCD (0.63)	SCDMEN1NPC1RAB9AKMT2A
	SCHEMBL10155145	0.88	HSD17B1 (0.53)	SCDNPC1RAB9ABACE1KDM4E
	SCHEMBL10156455	0.85	BACE1 (0.61)	SCDMEN1NPC1RAB9AKMT2A
	SCHEMBL10155483	0.81	BACE1 (0.70)	NPC1RAB9ABACE1KDM4EALDH1A1
	SCHEMBL4391114	0.80	SCD (1.00)	SCDMEN1NPC1RAB9AKMT2A
	SCHEMBL31243	0.80	SCD (1.00)	SCDMEN1NPC1RAB9AKMT2A
	SCHEMBL10157314	0.79	HSD17B1 (0.59)	BACE1
	SCHEMBL10156620	0.78	NPC1 (0.57)	MEN1NPC1RAB9AKMT2ABACE1
	SCHEMBL2955924	0.78	SCD (0.79)	SCDMEN1NPC1RAB9AKMT2A
	SCHEMBL10156025	0.78	BACE1 (0.69)	SCDMEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.