Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | KDM6A | O15550 | 3/20 | 0.59 |
| ▸ | KDM5A | P29375 | 3/20 | 0.59 |
| ▸ | KDM6B | O15054 | 1/20 | 0.59 |
| ▸ | KDM4A | O75164 | 1/20 | 0.59 |
| ▸ | KDM4B | O94953 | 1/20 | 0.59 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | KDM5C | P41229 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.59 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.59 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.59 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29409207 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KMT2AKDM4EKDM6AKDM5A | |
| SCHEMBL29374054 | 0.89 | KDM6A (0.59) | ALDH1A1KMT2AKDM4EKDM6AKDM5A | |
| SCHEMBL10157756 | 0.89 | KDM6A (0.59) | ALDH1A1KMT2AKDM4EKDM6AKDM5A | |
| SCHEMBL29409212 | 0.83 | KDM6A (0.64) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL18492972 | 0.83 | KDM6A (0.64) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL25189604 | 0.82 | KDM6A (0.62) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL18492977 | 0.82 | KDM6A (0.62) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL14931768 | 0.81 | KDM6A (0.61) | KMT2AKDM4EKDM6AKDM5AKDM6B | |
| SCHEMBL10158456 | 0.81 | KDM6A (0.60) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL18492980 | 0.80 | HDAC1 (0.66) | KMT2AKDM4EKDM6AKDM5AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962559-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | University of Houston System (US) | 2022-03-09 | — | — | EP | disclosed |
| CN-114007671-A | Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancer of epithelial tissue | 休斯敦大学体系 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020219963-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | UNIVERSITY OF HOUSTON SYSTEM (US) | 2020-10-29 | — | — | WO | disclosed |
| US-10206930-B2 | Methods for treating T-cell acute lymphoblastic leukemia | NEW YORK UNIVERSITY (US) | 2019-02-19 | — | — | US | disclosed |
| US-20170042904-A1 | METHODS FOR TREATING T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA | NEW YORK UNIVERSITY (US) | 2017-02-16 | — | — | US | disclosed |
| WO-2012052390-A1 | N-2-(2-PYRIDINYL)-4-PYRIMIDINYL-BETA-ALANINE DERIVATIVES AS INHIBITORS OF HISTONE DEMETHYLASE JMJD3 | GLAXO GROUP LIMITED (GB) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170042904-A1 | METHODS FOR TREATING T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA | KDM3A, KDM3B, KDM1B | ALDH1A1 1627/4885KMT2A 40/4885KDM4E 21/4885 |
| US-10206930-B2 | Methods for treating T-cell acute lymphoblastic leukemia | KDM3A, KDM3B, KDM1B | ALDH1A1 1627/4885KMT2A 40/4885KDM4E 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.