Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | KDM6A | O15550 | 3/20 | 0.59 |
| ▸ | KDM5A | P29375 | 3/20 | 0.59 |
| ▸ | KDM6B | O15054 | 1/20 | 0.59 |
| ▸ | KDM4A | O75164 | 1/20 | 0.59 |
| ▸ | KDM4B | O94953 | 1/20 | 0.59 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | KDM5C | P41229 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.59 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.59 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.59 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157580 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KMT2AKDM4EKDM6AKDM5A | |
| SCHEMBL29374054 | 0.89 | KDM6A (0.59) | ALDH1A1KMT2AKDM4EKDM6AKDM5A | |
| SCHEMBL10157756 | 0.89 | KDM6A (0.59) | ALDH1A1KMT2AKDM4EKDM6AKDM5A | |
| SCHEMBL29409212 | 0.83 | KDM6A (0.64) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL18492972 | 0.83 | KDM6A (0.64) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL25189604 | 0.82 | KDM6A (0.62) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL18492977 | 0.82 | KDM6A (0.62) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL14931768 | 0.81 | KDM6A (0.61) | KMT2AKDM4EKDM6AKDM5AKDM6B | |
| SCHEMBL10158456 | 0.81 | KDM6A (0.60) | KDM4EKDM6AKDM5AKDM6BKDM4A | |
| SCHEMBL18492980 | 0.80 | HDAC1 (0.66) | KMT2AKDM4EKDM6AKDM5AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962559-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | University of Houston System (US) | 2022-03-09 | — | — | EP | disclosed |