SCHEMBL10157967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10156396	0.91	BACE1 (0.47)	SMN1; SMN2KMT2ABACE1LMNAKDM4E
	SCHEMBL10155461	0.90	BACE1 (0.57)	SMN1; SMN2KMT2AMEN1SLC6A7BACE1
	SCHEMBL10156987	0.89	MAPK1 (0.56)	SMN1; SMN2BACE1LMNAKDM4ETSHR
	SCHEMBL10157908	0.84	KDM4E (0.54)	SMN1; SMN2KMT2AMEN1BACE1KDM4E
	SCHEMBL10155525	0.84	BACE1 (0.56)	BACE1ALDH1A1HPGD
	SCHEMBL10157290	0.83	BACE1 (0.54)	BACE1ALDH1A1HPGDCA12CA1
	SCHEMBL10155024	0.83	BACE1 (0.54)	BACE1ALDH1A1HPGD
	SCHEMBL10155033	0.83	L3MBTL1 (0.52)	SLC6A7BACE1KDM4ETSHRALDH1A1
	SCHEMBL10154605	0.82	BACE1 (0.55)	SMN1; SMN2KMT2ABACE1KDM4ETSHR
	SCHEMBL10156279	0.81	BACE1 (0.51)	SMN1; SMN2HSP90AA1KMT2AMEN1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.