Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158707 | 0.89 | EDNRA (0.36) | EDNRAMEN1KMT2ANPC1GAA | |
| SCHEMBL10158709 | 0.86 | RXFP1 (0.40) | EDNRAMEN1KMT2ANPC1GAA | |
| SCHEMBL10157239 | 0.84 | MEN1 (0.45) | EDNRAMEN1KMT2ANPC1GAA | |
| SCHEMBL15132897 | 0.77 | KDM4E (0.43) | EDNRAMEN1KMT2ANPC1GAA | |
| SCHEMBL10157235 | 0.76 | MEN1 (0.43) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12992704 | 0.75 | MEN1 (0.47) | EDNRAMEN1KMT2ANPC1GAA | |
| SCHEMBL15132898 | 0.74 | SMN1; SMN2 (0.41) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL10157230 | 0.73 | CYP3A4 (0.48) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL16258491 | 0.73 | CYP3A4 (0.48) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL12992709 | 0.71 | PSIP1 (0.45) | MEN1KMT2AGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220076-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2012-01-18 | — | — | EP | disclosed |