Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157230 | 1.00 | CYP3A4 (0.48) | CYP3A4PSIP1MEN1KMT2AHSD17B10 | |
| SCHEMBL10157239 | 0.89 | MEN1 (0.45) | CYP3A4PSIP1MEN1KMT2AHSD17B10 | |
| SCHEMBL10157235 | 0.88 | MEN1 (0.43) | CYP3A4PSIP1MEN1KMT2AHSD17B10 | |
| SCHEMBL13269047 | 0.85 | CYP3A4 (0.48) | CYP3A4PSIP1MEN1KMT2AHSD17B10 | |
| SCHEMBL10157257 | 0.83 | PSIP1 (0.43) | CYP3A4PSIP1NR1I2 | |
| SCHEMBL10157172 | 0.80 | GPR3 (0.37) | CYP3A4PSIP1MEN1KMT2AHSD17B10 | |
| SCHEMBL29985665 | 0.79 | CYP3A4 (0.59) | CYP3A4PSIP1MEN1KMT2AGAA | |
| SCHEMBL15416377 | 0.78 | PSIP1 (0.41) | CYP3A4PSIP1NR1I2 | |
| SCHEMBL12877159 | 0.78 | MEN1 (0.39) | CYP3A4PSIP1MEN1KMT2AHSD17B10 | |
| SCHEMBL30887308 | 0.78 | PSIP1 (0.57) | CYP3A4PSIP1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2757096-A9 | Inhibitors of human immunodeficiency virus replication | GILEAD SCIENCES, INC. (US) | 2014-11-26 | — | — | EP | disclosed |