Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 17/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 17/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902397 | 0.86 | AKR1C3 (0.59) | AKR1C3AKR1C2MEN1LMNAPOLB | |
| SCHEMBL902692 | 0.79 | AKR1C3 (0.64) | AKR1C3AKR1C2MEN1LMNAMAPT | |
| SCHEMBL902254 | 0.78 | AKR1C3 (0.72) | AKR1C3AKR1C2MEN1LMNAPOLB | |
| SCHEMBL13469244 | 0.77 | KDM4E (0.58) | MEN1LMNAPOLBMAPTKMT2A | |
| SCHEMBL4215631 | 0.77 | AKR1C3 (0.65) | AKR1C3AKR1C2MEN1LMNAPOLB | |
| SCHEMBL295164 | 0.76 | AKR1C3 (0.81) | AKR1C3AKR1C2MAPT | |
| SCHEMBL3484107 | 0.75 | APLNR (0.46) | POLBMAPTCYP1A2 | |
| SCHEMBL11070204 | 0.74 | KDM4E (0.54) | MAPTKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2305885 | 0.73 | KDM4E (0.57) | AKR1C3AKR1C2KMT2AKDM4ECYP1A2 | |
| Ammonia Solution, Strong SCHEMBL10346000 | 0.73 | APLNR (0.44) | POLBMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042265-A1 | NOVEL ACRIDINE DERIVATIVES | PHARMINOX LIMITED (GB) | 2012-04-05 | — | — | WO | disclosed |