SCHEMBL10159147

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18250108	0.93	MAPT (0.37)	MEN1KMT2AHTTUSP2MAPT
	SCHEMBL10194733	0.86	TRAP1 (0.41)	MEN1KMT2AHTTUSP2MAPT
	SCHEMBL10159270	0.86	MEN1 (0.41)	MEN1KMT2AHTTUSP2MAPT
	SCHEMBL10159094	0.85	MAPT (0.39)	MEN1KMT2AHTTUSP2MAPT
	SCHEMBL18250110	0.83	MAPT (0.37)	MEN1KMT2AHTTUSP2MAPT
	SCHEMBL10158919	0.83	KMT2A (0.50)	MEN1KMT2AHTTUSP2MAPT
	SCHEMBL10159199	0.83	TRAP1 (0.39)	MEN1KMT2AHTTUSP2MAPT
	SCHEMBL10159115	0.82	CHRM5 (0.38)	MEN1KMT2AMAPTGAATRAP1
	SCHEMBL10159193	0.81	KMT2A (0.39)	MEN1KMT2AHTTUSP2MAPT
	SCHEMBL10159175	0.81	TRAP1 (0.37)	TRAP1P2RX3HDAC1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.