Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 12/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12548476 | 0.86 | RAB9A (0.55) | MAPTLMNAALOX5APMAP4K4FEN1 | |
| SCHEMBL10160571 | 0.82 | ALOX5AP (0.49) | MAPTLMNAALOX5APMAP4K4FEN1 | |
| SCHEMBL29818212 | 0.82 | KIF11 (0.59) | MAPTLMNAALOX5APMAP4K4FEN1 | |
| SCHEMBL17164814 | 0.80 | PDE2A (0.54) | AKT1AKT2KDM4ENPC1RAB9A | |
| SCHEMBL10150538 | 0.79 | ALOX5AP (0.46) | ALOX5APFEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10161422 | 0.79 | ALOX5AP (0.47) | MAPTLMNAALOX5AP | |
| SCHEMBL20458847 | 0.78 | KDM4E (0.40) | ALOX5APMAP4K4FEN1KDM4EALDH1A1 | |
| SCHEMBL12019808 | 0.78 | MTOR (0.45) | MAPTLMNAALOX5APMAP4K4FEN1 | |
| SCHEMBL10161426 | 0.77 | ALOX5AP (0.49) | MAPTLMNAALOX5APFEN1 | |
| SCHEMBL17680282 | 0.74 | MKNK1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024150-A1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |