Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10161204 | 0.84 | HTR3A (0.50) | HTR3APDE4BJAK3 | |
| SCHEMBL10162739 | 0.78 | HTR3A (0.58) | HTR3APDE4BJAK3 | |
| SCHEMBL10162461 | 0.77 | HTR3A (0.53) | HTR3AMAPTPDE4BJAK3RAB9A | |
| SCHEMBL10161191 | 0.76 | HTR3A (0.56) | HTR3AJAK3 | |
| SCHEMBL10161127 | 0.75 | HTR3A (0.50) | HTR3APDE4BJAK3 | |
| SCHEMBL10163035 | 0.75 | MAPT (0.46) | HTR3AMAPTLRRK2RAB9A | |
| SCHEMBL6132417 | 0.74 | ADRB1 (0.56) | HTR3AMAPTRAB9A | |
| SCHEMBL6132422 | 0.74 | ADRB1 (0.56) | HTR3AMAPTRAB9A | |
| SCHEMBL10163027 | 0.74 | SLC18A3 (0.55) | HTR3AJAK3 | |
| SCHEMBL10163585 | 0.74 | HTR3A (0.53) | HTR3APDE4BJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | PANACEA BIOTEC LTD. (IN) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | CYP3A43, UGT1A1, CYP3A4 | HTR3A 852/4885MAPT 219/4885LRRK2 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.