Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.64 |
| ▸ | HPGD | P15428 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | GLA | P06280 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570407 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL2335762 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL1901476 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL10130703 | 0.82 | KDM4E (0.59) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL18754841 | 0.80 | KDM4E (0.57) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL1407731 | 0.79 | KDM4E (1.00) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL12200399 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL7305755 | 0.75 | KDM4E (0.52) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL10205883 | 0.73 | KDM4E (0.50) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL14730822 | 0.72 | CD38 (0.49) | ALDH1A1KDM4EHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061815-A1 | PYRIMIDONE DERIVATIVES CONTAINING TWO FUSED BICYCLIC RINGS | BASF SE (DE) | 2022-09-28 | — | — | EP | disclosed |
| WO-2021099240-A1 | PYRIMIDONE DERIVATIVES CONTAINING TWO FUSED BICYCLIC RINGS | BASF SE (DE) | 2021-05-27 | — | — | WO | disclosed |
| US-8906913-B2 | Azabicyclohexanes | PANACEA BIOTEC LIMITED (IN) | 2014-12-09 | — | — | US | disclosed |
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | PANACEA BIOTEC LTD. (IN) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | CYP3A43, UGT1A1, CYP3A4 | ALDH1A1 295/4885KDM4E 2799/4885HPGD 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.