Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163586 | 0.84 | MAPT (0.54) | MAPTNAMPT | |
| SCHEMBL10162449 | 0.82 | GAA (0.56) | MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10161329 | 0.80 | CHRNA7 (0.60) | MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10162738 | 0.80 | KMT2A (0.46) | MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10162628 | 0.80 | KMT2A (0.46) | MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10163589 | 0.79 | KMT2A (0.43) | MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10162843 | 0.78 | KMT2A (0.44) | MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10163033 | 0.78 | CA12 (0.52) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10161183 | 0.78 | SIGMAR1 (0.54) | MAPTKMT2AMEN1CYP2C19SMN1; SMN2 | |
| SCHEMBL10162854 | 0.78 | KMT2A (0.42) | MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | PANACEA BIOTEC LTD. (IN) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | CYP3A43, UGT1A1, CYP3A4 | TDP1 1083/4885MAPT 219/4885KMT2A 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.