Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 10/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198857 | 0.82 | GPR119 (0.57) | SIGMAR1TMEM97PDE4BSMN1; SMN2NPC1 | |
| SCHEMBL10161329 | 0.80 | CHRNA7 (0.60) | SIGMAR1SMN1; SMN2DRD1KDM4EGAA | |
| SCHEMBL9727540 | 0.79 | NPSR1 (0.68) | SIGMAR1TMEM97SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6132364 | 0.78 | GAA (0.69) | SIGMAR1TMEM97SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10243152 | 0.78 | MEN1 (0.62) | SIGMAR1TMEM97SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10162768 | 0.78 | TDP1 (0.57) | SMN1; SMN2MAPTCYP2C19MEN1KMT2A | |
| SCHEMBL10130954 | 0.77 | TMEM97 (0.51) | SIGMAR1TMEM97SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3960449 | 0.77 | SMN1; SMN2 (0.65) | SIGMAR1TMEM97SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4035554 | 0.77 | SMN1; SMN2 (0.72) | PDE4BSMN1; SMN2NPC1RAB9ACHRM4 | |
| SCHEMBL10163586 | 0.77 | MAPT (0.54) | PDE4BHTR1ALMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | PANACEA BIOTEC LTD. (IN) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | CYP3A43, UGT1A1, CYP3A4 | SIGMAR1 815/4885TMEM97 4343/4885PDE4B 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.