SCHEMBL418556

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL419000	0.90	SERPINE1 (0.60)	SERPINE1CNR1KDM4EGAANPC1
	SCHEMBL418577	0.89	SERPINE1 (0.73)	SERPINE1CNR1POLBKDM4EGAA
	SCHEMBL1015802	0.86	SERPINE1 (0.84)	SERPINE1CNR1POLBKDM4EGAA
	SCHEMBL1016838	0.85	SERPINE1 (0.81)	SERPINE1CNR1KDM4EGAANPC1
	SCHEMBL419148	0.84	SERPINE1 (0.82)	SERPINE1POLBKDM4EGAANPC1
	SCHEMBL1012933	0.83	SERPINE1 (0.61)	SERPINE1CNR1KDM4EGAAALDH1A1
	SCHEMBL1015662	0.83	SERPINE1 (0.64)	SERPINE1CNR1POLBKDM4EGAA
	SCHEMBL419057	0.82	SERPINE1 (0.78)	SERPINE1CNR1NPC1ALDH1A1HPGD
	SCHEMBL1015090	0.82	SERPINE1 (0.79)	SERPINE1CNR1NPC1ALDH1A1HPGD
	SCHEMBL417046	0.81	SERPINE1 (0.47)	SERPINE1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.