SCHEMBL10162929

SCHEMBL10162929

CC(c1ccc(C(C)c2ccc(N(C)c3ccccc3)cc2)cc1)c1ccc(N(C)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 1/20 0.44
ESR1 P03372 1/20 0.41
PDCD1 Q15116 1/20 0.41
ESR2 Q92731 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
MAPK1 P28482 2/20 0.41
S1PR4 O95977 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HPGD P15428 1/20 0.41
S1PR1 P21453 1/20 0.41
CCR6 P51684 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TLR9 Q9NR96 1/20 0.41
CHKA P35790 3/20 0.40
PTPN1 P18031 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32689850 1.00 NR3C2 (0.44) NR3C2ESR1PDCD1ESR2CD274
SCHEMBL17754486 0.98 NR3C2 (0.43) NR3C2ESR1PDCD1ESR2CD274
SCHEMBL13570261 0.94 ALDH1A1 (0.43) NR3C2ESR1PDCD1ESR2CD274
SCHEMBL13570273 0.88 CES1 (0.42) SMN1; SMN2ALDH1A1LMNACES1KDM4E
SCHEMBL13539185 0.87 CHKA (0.47) NR3C2MEN1KMT2AMAPK1CHKA
SCHEMBL13333786 0.86 ALDH1A1 (0.45) NR3C2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL9659560 0.84 NR3C2 (0.46) NR3C2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL15998818 0.84 ALDH1A1 (0.50) ESR1PDCD1ESR2CD274MEN1
SCHEMBL7155149 0.83 NR3C2 (0.56) NR3C2SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL4669767 0.82 ALDH1A1 (0.50) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173343-B2 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
US-7964327-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming apparatus, image forming method and process cartridge using the photoreceptor RICOH COMPANY LTD. (JP) 2011-06-21 US disclosed
US-7729634-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2010-06-01 US disclosed
US-20100015538-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS USING THE SAME, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2010-01-21 US disclosed
US-20080219694-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-09-11 US disclosed
US-20080113285-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-05-15 US disclosed
US-20080112742-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-05-15 US disclosed