Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145543 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| SCHEMBL3893552 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| SCHEMBL17754486 | 0.84 | NR3C2 (0.43) | ALDH1A1KDM4EMAPK1TDP1HPGD | |
| SCHEMBL7110610 | 0.84 | SLC2A1 (0.61) | ALDH1A1TSHRHSD17B10KDM4EALOX15 | |
| SCHEMBL61350 | 0.84 | SLC2A1 (0.61) | ALDH1A1TSHRHSD17B10KDM4EALOX15 | |
| SCHEMBL8643448 | 0.83 | ESR1 (0.55) | ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL10116476 | 0.82 | ALDH1A1 (0.68) | ALDH1A1TSHRHSD17B10KDM4EALOX15 | |
| SCHEMBL9180847 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10KDM4EALOX15 | |
| Water SCHEMBL10498815 | 0.82 | SLC2A1 (0.59) | ALDH1A1TSHRHSD17B10KDM4EALOX15 | |
| SCHEMBL10162929 | 0.82 | NR3C2 (0.44) | ALDH1A1KDM4EMAPK1TDP1RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | DAICEL CHEMICAL INSDUSTRIES, LTD. (JP) | 2008-09-11 | — | — | US | disclosed |
| EP-1967505-A1 | Process for the preparation of substituted phenols | Daicel Chemical Industries, Ltd. (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-5081191-A | Functionalized polymers prepared by anionic polymerization | THE DOW CHEMICAL COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4975491-A | Functionalized polymers prepared by anionic polymerization | THE DOW CHEMICAL COMPANY (US) | 1990-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | CYP1A1, NOX1, ROS1 | ALDH1A1 308/4885TSHR 3848/4885HSD17B10 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.