Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.39 |
| ▸ | TUBB | P07437 | 8/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132804 | 0.92 | CYP19A1 (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10163174 | 0.87 | PDE3B (0.45) | CYP19A1NQO2ACHEPDE3BPDE3A | |
| SCHEMBL10163171 | 0.85 | CYP19A1 (0.41) | CYP19A1NQO2ACHEKDRALDH1A1 | |
| SCHEMBL10163184 | 0.83 | CYP19A1 (0.40) | CYP19A1NQO2ACHEPDE3BPDE3A | |
| SCHEMBL10163291 | 0.83 | ALDH1A1 (0.40) | CYP19A1NQO2ACHEKDRALDH1A1 | |
| SCHEMBL10163000 | 0.81 | GAA (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10161825 | 0.80 | NPC1 (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10161780 | 0.78 | CYP19A1 (0.37) | CYP19A1NQO2KDRALDH1A1 | |
| SCHEMBL10132697 | 0.77 | CYP19A1 (0.41) | CYP19A1NQO2KDRALDH1A1 | |
| SCHEMBL10163662 | 0.76 | RXFP1 (0.40) | ACHEALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | TUBB4A 1365/4885TUBB 2301/4885TUBA3C 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.