Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 3/20 | 0.53 |
| ▸ | CDC42 | P60953 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ATP2A1 | O14983 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163107 | 0.94 | RAC1 (0.56) | RAC1CDC42ALDH1A1MAPTHPGD | |
| SCHEMBL10132677 | 0.92 | RAC1 (0.44) | RAC1CDC42ALDH1A1MAPTHPGD | |
| SCHEMBL10132283 | 0.83 | RAC1 (0.39) | RAC1CDC42ALDH1A1MAPTHPGD | |
| SCHEMBL10132680 | 0.81 | RAC1 (0.45) | RAC1CDC42ALDH1A1MAPTHPGD | |
| SCHEMBL10132274 | 0.77 | RAC1 (0.41) | RAC1CDC42ALDH1A1MAPTHPGD | |
| SCHEMBL10161703 | 0.76 | ALDH1A1 (0.31) | RAC1CDC42ALDH1A1MAPTHPGD | |
| SCHEMBL13284428 | 0.75 | RAC1 (0.78) | RAC1CDC42ALDH1A1MAPTHPGD | |
| SCHEMBL10162982 | 0.74 | RAC1 (0.55) | RAC1CDC42ALDH1A1MAPTHPGD | |
| SCHEMBL10163286 | 0.73 | RAC1 (0.49) | RAC1CDC42ALDH1A1MAPTHPGD | |
| SCHEMBL13284349 | 0.72 | RAC1 (0.53) | RAC1CDC42ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | RAC1 1000/4885CDC42 747/4885ALDH1A1 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.