Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10131245 | 0.82 | MTOR (0.43) | MTORPIK3CA | |
| SCHEMBL23583667 | 0.73 | GRM5 (0.42) | — | |
| SCHEMBL16887480 | 0.72 | DRD2 (0.46) | MTORPIK3CA | |
| SCHEMBL10162703 | 0.72 | NOS3 (0.46) | MTORPIK3CA | |
| SCHEMBL14850538 | 0.71 | MTOR (0.40) | MTORPIK3CA | |
| SCHEMBL19775310 | 0.70 | MTOR (0.44) | MTORPIK3CA | |
| SCHEMBL503292 | 0.69 | MTOR (0.44) | MTORPIK3CA | |
| SCHEMBL29571687 | 0.69 | MTOR (0.44) | MTORPIK3CA | |
| SCHEMBL28773559 | 0.69 | APP (0.42) | — | |
| SCHEMBL23583671 | 0.69 | CYP2A6 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035352-A1 | 6-11 Bicyclic Ketolide Derivatives | OR YAT SUN (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035352-A1 | 6-11 Bicyclic Ketolide Derivatives | AKR1C2, AKR1C3, AKR1C1 | MTOR 920/4885PIK3CA 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.