SCHEMBL10164213

SCHEMBL10164213

CON1C(C)(C)CC(OCC(O)CN2C(C)(C)CCCC2(C)C)CC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
CYP2D6 P10635 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10164295 0.86 KMT2A (0.40) LMNAKMT2AMEN1CYP2D6HTT
SCHEMBL10164216 0.81 KMT2A (0.33) KMT2AMEN1CYP2D6
SCHEMBL10164214 0.80 KMT2A (0.34) KMT2AMEN1CYP2D6
SCHEMBL17350835 0.80 MEN1 (0.32) KMT2AMEN1
SCHEMBL10201407 0.79 KMT2A (0.32) KMT2AMEN1CYP2D6
SCHEMBL10164215 0.77 KMT2A (0.31) KMT2ACYP2D6
SCHEMBL10164356 0.75 ADH1C (0.32) KMT2A
Bicarbonate SCHEMBL3798404 0.75 KMT2A (0.34) KMT2AMEN1
SCHEMBL10968210 0.74 LMNA (0.58) LMNATP53KMT2AMEN1CYP2D6
SCHEMBL10968977 0.74 KMT2A (0.38) LMNATP53KMT2AMEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120083557-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2012-04-05 US disclosed
US-20120083557-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2012-04-05 US disclosed
WO-2010142572-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2010-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120083557-A1 STERICALLY HINDERED AMINE STABILIZERS AAAS, H1-5, H1-2 LMNA 1890/4885TP53 1959/4885KMT2A 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.