Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101283 | 0.82 | KMT2A (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL101662 | 0.81 | MEN1 (0.38) | KMT2AMEN1ALDH1A1VCAM1SMN1; SMN2 | |
| SCHEMBL101643 | 0.77 | CYP2D6 (0.37) | KMT2AMEN1ALDH1A1BRD4 | |
| SCHEMBL4021394 | 0.74 | MEN1 (0.55) | KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL4296859 | 0.73 | MEN1 (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL9815014 | 0.72 | MEN1 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL9815017 | 0.72 | MEN1 (0.55) | KMT2AMEN1ALDH1A1CYP2C9 | |
| Potassium Ion SCHEMBL4296985 | 0.72 | MEN1 (0.55) | KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL28948590 | 0.72 | MEN1 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP2C9 | |
| Potassium Ion SCHEMBL30084855 | 0.72 | MEN1 (0.55) | KMT2AMEN1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9441270-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150344950-A1 | Functionalized Cyanine Dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-12-03 | — | — | US | disclosed |
| US-9051263-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20150072894-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| US-8889886-B2 | Cyanine dyes | PACIFIC BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-8669374-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2014-03-11 | — | — | US | disclosed |
| US-20120058469-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | KMT2A 2564/4885MEN1 2288/4885ALDH1A1 1447/4885 |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | ACR, IK, EGFR | KMT2A 3543/4885MEN1 3947/4885ALDH1A1 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.