Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971604 | 0.79 | GRM2 (0.38) | GRM2APPCYP2C9ALOX5APFEN1 | |
| SCHEMBL9022369 | 0.78 | KMT2A (0.44) | APPCYP3A4 | |
| SCHEMBL10164561 | 0.76 | CYP3A4 (0.45) | APPCYP2C9ALOX5APFEN1CYP3A4 | |
| SCHEMBL9020090 | 0.74 | GRM2 (0.30) | GRM2 | |
| SCHEMBL9019624 | 0.74 | APP (0.35) | APPALOX5APFEN1 | |
| SCHEMBL10153192 | 0.74 | RORC (0.35) | GRM2APPCYP2C9CYP3A4 | |
| SCHEMBL12999700 | 0.74 | CYP3A4 (0.37) | APPCYP2C9CYP3A4 | |
| SCHEMBL17070284 | 0.73 | ALOX5AP (0.35) | GRM2APPCYP2C9ALOX5APFEN1 | |
| SCHEMBL12999862 | 0.72 | APP (0.40) | APPCYP2C9CYP3A4 | |
| SCHEMBL20380654 | 0.72 | GRM2 (0.32) | GRM2APPCYP2C9ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |