Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 8/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | LCT | P09848 | 2/20 | 0.33 |
| ▸ | UGCG | Q16739 | 2/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10153192 | 0.82 | RORC (0.35) | APPBRD4CHKA | |
| SCHEMBL13586444 | 0.80 | BRD4 (0.36) | DRD4SIGMAR1TMEM97BRD4ALOX5AP | |
| SCHEMBL13586446 | 0.80 | BRD4 (0.35) | BRD4ALOX5APFEN1NAAA | |
| SCHEMBL8970624 | 0.79 | DRD4 (0.41) | APPDRD4SIGMAR1TMEM97CHKA | |
| SCHEMBL13586347 | 0.79 | BRD4 (0.35) | DRD4SIGMAR1TMEM97BRD4ALOX5AP | |
| SCHEMBL12823814 | 0.79 | NAAA (0.38) | DRD4SIGMAR1TMEM97BRD4ALOX5AP | |
| SCHEMBL12999862 | 0.78 | APP (0.40) | APP | |
| SCHEMBL12907934 | 0.78 | RARB (0.37) | BRD4CHKA | |
| SCHEMBL10164561 | 0.78 | CYP3A4 (0.45) | APPALOX5APFEN1 | |
| SCHEMBL12823495 | 0.76 | BRD4 (0.34) | APPDRD4SIGMAR1TMEM97BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |