Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220616 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL2477200 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL10164617 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL2478799 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL14813298 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL13263958 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL6741809 | 0.85 | ALDH1A1 (0.35) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL6743066 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL17226939 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL2479685 | 0.84 | P2RX7 (0.38) | ALDH1A1TP53TSHRHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173631-B2 | Cyclic amine compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20110319468-A1 | CYCLIC AMINE COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319468-A1 | CYCLIC AMINE COMPOUNDS | RYR2, CASR, RYR1 | ALDH1A1 2584/4885TP53 3433/4885TSHR 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.