SCHEMBL10165696

SCHEMBL10165696

c1ccc(-c2ccc3sc4c(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)cc(-c5ccccc5)cc4c3c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
LIMK1 P53667 2/20 0.38
TSPO P30536 1/20 0.35
PIM3 Q86V86 2/20 0.34
ALOX5 P09917 1/20 0.34
HDAC4 P56524 1/20 0.33
KMT2A Q03164 2/20 0.33
IL1R1 P14778 1/20 0.33
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
PTGER4 P35408 1/20 0.32
PIM1 P11309 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10165712 0.98 L3MBTL1 (0.41) L3MBTL1KDM4EATMLIMK1TSPO
SCHEMBL10165744 0.98 L3MBTL1 (0.43) L3MBTL1KDM4EATMLIMK1TSPO
SCHEMBL10165730 0.96 LIMK1 (0.40) L3MBTL1KDM4EATMLIMK1TSPO
SCHEMBL13830037 0.95 KDM4E (0.38) L3MBTL1KDM4EATMLIMK1TSPO
SCHEMBL780694 0.94 KDM4E (0.37) L3MBTL1KDM4EATMLIMK1TSPO
SCHEMBL10165720 0.94 L3MBTL1 (0.42) L3MBTL1KDM4EATMLIMK1TSPO
SCHEMBL781299 0.93 KDM4E (0.36) L3MBTL1KDM4EATMLIMK1TSPO
SCHEMBL780682 0.93 KDM4E (0.36) L3MBTL1KDM4EATMLIMK1TSPO
SCHEMBL17166669 0.93 L3MBTL1 (0.41) L3MBTL1KDM4EATMLIMK1TSPO
SCHEMBL780827 0.92 KDM4E (0.35) L3MBTL1KDM4EATMLIMK1TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element NUTF2, BRI3BP, CLINT1 L3MBTL1 1016/4885KDM4E 2172/4885ATM 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.